Lactation hormone helps a mother's brain

28 September 2017

The same hormone that stimulates milk production for lactation, also helps to establish the nurturing link between mother and baby, University of Otago researchers have revealed for the first time.
The researchers found that the hormone prolactin which stimulates milk production also sends signals to the brain which are essential for mothers to show vitally important maternal nurturing behaviour towards their young.

This finding raises the question, is this brain circuitry the “feel good” factor to encourage breast feeding?
The research team at the University’s Centre for Neuroendocrinology looked at the hormone in mice and deleted prolactin receptors in the preoptic area of the brains of adult female mice.
Study co-author Dr Rosie Brown says the team observed that the mice without prolactin receptors were able to get pregnant and give birth normally, but abandoned their litters around 24 hours after birth.
“Our findings establish a critical role for prolactin for more than simply milk production.  This work is the first to show this hormone is a literal life saver in that it establishes and maintains the normal parental care that ensures offspring survival.”

Disruptions in the ability of prolactin to communicate in the brain could lead to problems for mothers establishing a bond with their baby. This may in part explain issues with some animal species abandoning their young, she says.